Customer Testimonials
Dr. Michael Mathis Louisiana State University
Health Sciences Center, USA
“My work focuses on the
development of adenovirus-based vectors for immunotherapy of breast
cancer, using mouse models of the disease. ProImmune’s REVEAL™ Rapid
Epitope Discovery System has provided a cost-effective method for me to
screen my proteins of interest for potentially immunogenic epitopes. I
have been particularly impressed with the service that ProImmune offers,
so much so that I’ve been telling my colleagues that they too should
outsource more of their routine experiments to experts in order to free up
their time. It really saves time and money when one take into account the
effort needed to set up these assays in house and then wait for results. I
will definitely be using the system again to obtain further data on the
hits from the first round of screening.”
Dr. John Webb British Columbia Cancer Agency,
Canada
“Over the past
six years I have been using ProImmune’s
Pro5® Pentamers for the
identification and characterization of tumour epitope-specific T cells.
Pentamers play an important role in my work to
develop new
vaccine strategies to induce T cell-mediated immune responses directed
against human malignancies. I am always impressed by the knowledge and
friendliness of the customer service team, and find the website
very user-friendly and well-organized."
Dr. Yared Haliemichael University of Texas MD Anderson Cancer
Center, USA
“I use the B16 melanoma/pmel-1 T cell model to study the requirements
for successful vaccination using peptide immunogens. The induction of
strong CD8 T cell response requires a sustained presentation of antigen in
a stimulatory context to develop into effector cells that can kill tumors
through the recognition of tumor antigens bound to MHC-I molecules. It is
important to have a high standard of reagents for my mouse vaccination
protocols, and I am very satisfied with the quality of peptides and the
responsive customer service that thinkpeptides provides.” (thinkpeptides
is ProImmune's brand for custom peptide synthesis services)
Dr.Cath Bollard Baylor college of Medicine, Houston, USA
"Pro5® MHC Pentamers have played an important part in our study on adoptive immunotherapy for cancer and viral infections, post-transplant. We use Pentamers to detect and quantify the populations of antigen-specific T cells in CTL lines made for clinical use. We also use them to detect antigen-specific CTL in the peripheral blood of transplant patients, pre and post-CTL-infusion. The Pentamers were chosen for their stability and for the increased intensity and specificity of the positive population compared to MHC tetramers. We have found Pentamers to be consistent and reliable, and ProImmune's customer service is excellent".
Prof. Thomas Brocker Institute for Immunology, University of Munich, Germany
"ProImmune Pro5® MHC Pentamers have been influential in our research to analyze CD8 T cell responses in vivo. Colleagues in the lab recommended the Pentamers to us. For the past two years we have used them for flow cytometry applications to achieve reliable staining across different batches of the same product. I can also recommend ProImmune for their easy ordering process and excellent customer service".
Prof. Dirk Schlueter Otto-von-Guericke Universitaet, Magdeburg, Germany
"I have used ProImmune's Pro5® MHC Pentamers in my immunology research into infectious diseases in murine models. Using the Pentamers in flow cytometry, I have found them to be of good quality and easy to use. Over the past 3 years I have had a positive experience with the company and have found them to be competitively priced and swift to manufacture and deliver their products".
Dr. Behazine Combadière CHU Pitié-Salpétrière, Paris, France
"I have used Pentamers from ProImmune in flow cytometry applications over the last two years. My decision to use Pentamers was based on the good quality, reliability and reasonable price for the products".
Dr. Vesna Blazevic FIT Biotech, Finland
"ProImmune's PEPscreen® library has played a central role in my research into DNA based and HIV vaccines in both IFN gamma and IL-2 ELISPOT assays. Working in preclinical and clinical settings, I have found the library to be an easy and reliable way of screening for T cell epitopes. The peptides were easy to dissolve, of a very good quality and showed no non-specific background in the ELISPOT assay. My decision to purchase products from ProImmune was based on the fact that they are a good price, of a superior quality and have fast delivery. I look forward to using ProImmune's products in my future research".
Dr. Johannes Wiegand University of Leipzig, Germany
"My research is investigating the T cell immunology of viral hepatitis. Using PEPscreen® overlapping peptides from ProImmune in IFN gamma ELISPOT and 3H-proliferation assays, enabled us to map the entire Hepatitis B surface antigen and HBV-core antigen region for T cell analysis. ProImmune was personally recommended to me by Dr. Heiner Wedemeyer and true to his recommendation, I found their peptides to be of a very good quality and easy to use. The administrative team were very helpful with the process of billing and shipping and I had good communication with my account manager who made useful comments and was highly motivated to solve any issues that arose".
Dr. Karen Fitzmaurice Institute of Molecular Medicine, Trinity College Dublin, Ireland
"Our study aimed to characterize the CD8+ T cell responses associated with certain class I alleles linked to favourable outcomes in HCV infection. We chose a PEPscreen®: Custom Peptide Library of overlapping peptides spanning the HCV genome to use in ELISPOT assays. As well as the fact that the peptide library was of good quality and easy to reconstitute for use in the assays, I also found the price to be competitive and the service I received was excellent".
Dr. Haifeng Song Novavax, USA
"My research involves detecting T cell responses triggered by vaccine candidates. I used peptides from a PEPscreen®: Custom Peptide Library to stimulate cells in vitro and then studied cytokine secretion by T cells using ELISPOT and intracellular staining. I found the peptide library to be of good quality, and the ProImmune team were very professional in terms of their knowledge of the field and their helpful attitude".
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