Figure: ProM1™ Monomer
ProM1™ Class I MHC Monomers are provided already biotin labeled and can be readily adapted to implement specialist solid or solution phase immunoassays or for measuring interactions of predefined MHC Class I-peptide complexes with ligands such as monoclonal antibodies, recombinant T cell receptors, or other binding scaffolds, e.g. for use in screening of novel antigen-specific CAR T cell antigen receptors.
ProM1™ MHC Monomers are made by ProImmune’s experienced team who have been providing superior MHC reagents for more than 18 years now, including our world-leading Pro5® MHC Class I Pentamers.
ProImmune provides ProM1™ Class I MHC Monomers with responsive, expert technical support and customer service. Contrary to ordering class I monomers from in-house or non-commercial facilities, customers do not need to apply and wait for reagents or supply any peptide. ProM1™ Class I MHC Monomers are delivered quickly with stringent quality control and low batch-to-batch variability. As such, ProM1™ Class I MHC Monomers complement ProImmune’s existing Pro5® Class I Pentamer technology for detecting antigen-specific CD8+ T cells.
35ug, 100ug; please contact us for larger quantities
Catalog ProM1™ Monomers are available within 1-2 weeks of placing an order.
Custom ProM1™ Monomers for your allele/peptide of interest are available within approximately 6-7 weeks from ordering. Peptide sequences are subject to prior evaluation by ProImmune for binding. Once a peptide sequence is accepted for custom synthesis we will synthesize both the peptide and MHC monomer reagent.
HLA-A*01:01, A*02:01, A*03:01, A*11:01, A*24:02
HLA-B*07:02, B*08:01, B*35:01
H-2 Kb, Kd, Db, Ld
If your allele is not on the list above, please enquire.