Citrullination modulates antigen processing and presentation by revealing cryptic epitopes in rheumatoid arthritis

Ashley Curran recently received her PhD in Immunology from the Johns Hopkins University School of Medicine and is now a Postdoctoral Fellow at the Medical University of Vienna. Her doctoral research focused on the molecular mechanisms underlying the pathogenesis of citrullination-directed autoimmunity in rheumatoid arthritis, with a particular focus on the role of MHC class II antigen processing and presentation in the loss of CD4+ T cell tolerance.