Introducing: ProT2™ MHC Class II Tetramers

ProImmune Introduces ProT2MHC Class II Tetramer Reagents to Study Antigen-Specific CD4+ T Cell Immune Responses

Oxford, UK, 14 January 2016 


ProImmune, a leader in services for understanding and managing adaptive
immune responses, announced today the introduction of ProT2,
a range of Human MHC Class II tetramer reagents for tetramer analyses in
the study of antigen-specific CD4+ T cell immune responses. ProImmune’s
offering represents the broadest choice of ready to order catalog and
custom items in this field and will enable research into CD4+ T cell
responses in a variety of disease areas including cancer, infectious
diseases, allergy, autoimmunity and transplantation. Another key area
for this product range is the detailed study of T cell help in unwanted
immune responses to biologics.

CD4+ T cell
responses are at the heart of steering the adaptive immune system
directing both cytotoxic T cell responses and antibody responses
mediated by B cells. ProT2™ MHC Class II Tetramers allow the direct
detection and separation of single antigen-specific CD4+T cells
accurately by flow cytometry.

Nikolai Schwabe, CEO of ProImmune commented: “By introducing a broad and growing
ProT2™ Tetramer product range we intend to give MHC Class II tetramer
analysis the emphasis  it deserves in the study of CD4+ T cell responses
which play such a pivotal role in adaptive immunity across so many
disease and treatment modalities.”

ProT2™ Class II MHC Monomer reagents are supported by ProImmune’s expert
customer service and application support, helping new users in
particular to establish and optimize robust protocols in their own
laboratories.

This addition to ProImmune’s class II reagent offering further complements an
already extensive range of services for evaluating CD4+ T cell
responses, including ProImmune REVEAL® MHC peptide binding assays, CD4+
T cell and DC T cell proliferation assays and standard immune monitoring
services through ELISPOT and flow cytometry based assays.

For more information on ProT2™ reagents and their availability, or to place an
order, please visit:


www.proimmune.com

email enquiries@proimmune.com, or call + 1 888 505 7765 in the United States or + 44 870 042 7279 in other countries.

 

-ENDS-

Notes to Editors:

About ProImmune –
www.proimmune.com

ProImmune’s mission is to
be a partner of choice for understanding and managing adaptive immune
responses. It does this by offering unique solutions for preclinical and
clinical immunology research, including a comprehensive and integrated
antigen characterization and immunogenicity testing platform, and
products and services for tracking antigen-specific immune responses
with state-of-the-art ELISpot and flow cytometry techniques. ProImmune
is committed to helping researcher’s achieve success through product
innovation, responsive service and focused application support, saving
time and money, and reducing risk.

For more information, please contact

At ProImmune:

Jeremy Fry,

Tel: +44 (0) 870 042 7279

Email: enquiries@proimmune.com

Media enquiries:

Sarah Jeffery

Zyme Communications Ltd

Tel: +44 (0) 7771 730 919

Email: sarah.jeffery@zymecommunications.com