Mastering Immunity 2019

Monday 9 September – Tuesday 10 September

Museum of Science, Boston
Register today

Early bird discount ends August 2, 2019

A unique opportunity to meet with a listen to world-leading immunologists present their latest work. Presentations from our meetings are available online free of charge.

Understand and manage immune responses in drug and vaccine development

As targeted immune therapies grow in complexity, understanding and controlling immune regulation has never been more important in the design of therapeutics.

Join experts in both academic and commercial immunology at Mastering Immunity 2019 for a focussed conference to learn the latest developments in this fast-developing field covering multiple aspects of in the development of modern therapeutics. This focussed meeting is a forum for key people involved in wanting to characterize immune modulation following delivery of biologics and other therapies to come together to share knowledge, perspectives and discuss solutions to the complex challenges of immunity in this context. We will focus on manipulation and characterization of both desired (in immuno-oncology and vaccines) as well as unwanted immune responses (i.e. immunogenicity to biotherapeutics or viral vectors).

This year’s meeting in Cambridge, MA, is now in its eighth consecutive year having also been held in Oxford, UK. It offers an unparalleled opportunity to meet are share information with like-minded scientists from other organisations, and to help shape the future of your R&D programs.

Programme

Monday September 9

Time	Speaker	Title
08.45		Registration opens / coffee
09.15		Introduction
09.25	Dr. Patrick Hanley, Director of GMP for Immunotherapy, Children's National, Washington DC	Antiviral T cells derived from the naïve population for patients post-transplant
10.05	Dr. Ruben Hoogeveen, Massachusetts General Hospital	Tracking HBV immunity: identification and characterization of new MHC class I and II T cell epitopes
10.45		Coffee and networking
11.15	Prof. Beatriz Carreno, Parker Institute for Cancer Immunotherapy, University of Pennsylvania	Dissecting Melanoma Neoantigen Immunity
11.55	Prof. Karen Anderson, Arizona State University	The Challenge of Measuring Antigenic Diversity
12.35pm		Lunch and Networking Museum Exhibits open
2.15pm	Dr. Emilee Knowlton, ProImmune	Epitope identification and clinical immune monitoring in immune oncology programs
2.55pm	Dr. Rao Prabhala, Harvard Medical School	Detailed Characterization of Immune Bio-Markers in Cancer Patients
3.35pm		Coffee and networking
4.05pm	Dr. Paul Arnaboldi, New York Medical College	Using peptide-based assays to improve the laboratory diagnosis of Lyme disease
4.45-6.15pm		Networking Drinks

Tuesday September 10

Time	Speaker	Title
09.00	Dr. Katerina Alexaki, FDA	Effects of codon optimization on biotherapeutics: Implications for immunogenicity
09.40	Dr. Jeremy Fry, ProImmune	An Integrated Approach to Managing Immunogenicity Risk and Optimum Protein Design
10.20		Coffee and networking
11.00	Dr. Andrea Ferrante, Eli Lilly	Assessment of MHC class II-restricted epitope prediction in silico
11.40	Dr. Sophie Tourdot, Pfizer	Deployment of the immunogenicity risk assessment assay-suite for protein design, risk assessment and de-immunization
12.20pm		Lunch and Networking Museum Exhibits open
1.45pm	Dr. Inderpal Singh, TEVA Pharmaceuticals	Immunogenicity risk assessment of peptide-related impurities: Current Strategies & its Challenges
2.25pm	Dr. Vibha Jawa, Merck & Co.	Implementation of risk assessment outputs to drive clinical immunogenicity strategy and regulatory filing-related activities
3.05pm		Meeting close

Speakers from past meetings include

Prof. Fiona Powrie, Oxford University, Oxford, UK
Prof. Arlene Sharpe, Harvard University, Cambridge, MA
Prof. Ethan Shevach, NIH/NIAID, Bethesda, MD
Prof. Herman Waldmann, Oxford University, Oxford, UK
Prof. Farzin Farzeneh, Kings College London, London, UK
Dr. Amy Rosenberg, FDA, Bethesda, MD

How will I benefit?

Education

Network

Learn the key issues facing drug developers
Be informed of the latest strategies for preclinical and clinical immune modulation
Quality by Design in drug development
Be informed of the latest strategies for pre-clinical and clinical immune modulation
Case studies

- Exchange new ideas
- Meet potential collaborators
- Discuss current and developing challenges

Meet like-minded scientists from other organizations, and to help shape the future of your own R&D programs.

Feedback from previous conferences:

“Mastering Immunogenicity captured the breadth and depth of immunogenicity issues faced by industry today” (Tim Hickling, Pfizer)

“I absolutely enjoyed the talks and very much liked the small and highly interactive fomat of the meeting. The quality of the program was very high and I indeed picked up some useful ideas that I am incorporating into our programs.” (Shahla Abodollahi, Celgene)

“It has been a terrific opportunity to learn more about immunology, and immunogenicity in particular, from esteemed colleagues in the field, interacting with them and sharing some of my views on the topic. I look forward to more of these.” (Andrea Ferrante, Eli Lilly)

“I also had a great time during the meeting. It was truly excellent in content and organization.” (Julio Delgado, University of Utah)

“It was a terrific event, with excellent speakers and great networking/brainstorming opportunities at the breaks and with the roundtable” (Valerie Quarmby, Genentech)

“Great first experience. I enjoyed the breadth of topics” (Laurent Malherbe, Eli Lilly)

“Great speakers with diverse topics. I enjoyed the deep science and also the opinions from experts in the field” (Xiaoying Chen, Pfizer)

“Covered a diverse array of subjects. I enjoyed the networking opportunities” (Shinu John, Moderna Therapeutics)

“Excellent event” (George Gunn, Janssen R&D)

“Really liked the interactive environment. In-depth discussions with very relevant colleagues”

“I really enjoyed the very good quality, sparkling diversity, but still keeping focus”

“Very nice and comprehensive topics in this symposium. I have learnt a lot from it.” (Pu Shi, Takeda)

“This is a fantastic conference that is a good mix of vaccine and biotherapeutic folks. Facilitates learning and collaboration.” (Priya Sriraman, Celgene)

Conference Venue

Boston Museum of Science, 1 Science Park, Boston, MA 02114

The city of Boston is an international center of higher education and a center for medicine and biotechnology, and consequently is a fitting location for ProImmune’s Mastering Immunity conference. The venue is the Museum of Science, one of the world’s largest science centers, and New England’s most highly attended cultural institution.

The meeting will take place in the Skyline Room on the Museum’s top floor, with panoramic views of the Charles River, Back Bay, Boston and Cambridge through two walls of floor-to-ceiling windows.

Accommodation

Delegates are responsible for arranging their own accommodation. The following are suggested options for accommodation in the vicinity of the conference venue:

Royal Sonesta Hotel

Kimpton Hotel Marlowe

Fairfield Inn & Suites by Marriott

Hampton Inn Boston Cambridge