Oxford

Mastering Immunity Europe 2017

Thursday 23 and Friday 24 March 2017

Wolfson College, Oxford, UK

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Understand and manage immune responses in drug and vaccine development

As targeted immune therapies grow in complexity, understanding and controlling immune regulation has never been more important in the design of therapeutics.

Join experts in both academic and commercial immunology at Mastering Immunity Europe 2017 for a focussed conference to learn the latest developments in this fast-developing field covering multiple aspects of in the development of modern therapeutics. This focussed meeting is a forum for key people involved in wanting to characterize immune modulation following delivery of biologics and other therapies to come together to share knowledge, perspectives and discuss solutions to the complex challenges of immunity in this context. We will focus on manipulation and characterization of both desired (in immuno-oncology and vaccines) as well as unwanted immune responses (i.e. immunogenicity to biotherapeutics or viral vectors).

This meeting, of which the Mastering Immunogenicity series is part of, is now in its seventh consecutive year having also been held in Cambridge, USA.  Free access to all recorded talks can be found here. This event in Oxford offers an unparalleled opportunity to meet and share information with like-minded scientists from other organizations, and to help shape the future of your R&D programs.

Full Programme details including Abstracts and Speaker information can be found here.

Programme

Thursday 23 March 2017

8.30am

Arrival, registration and refreshments

8.50am

Welcome and conference overview

9.00am

Dr. Bernard Maillère

CEA, France

Specificity and phenotype of pre-existing T cells raised against therapeutic proteins in healthy donors

9.40am

Mr. Marco Hofmann

CSL Behring, Germany

In vitro assessment of the potential immunogenicity of Astyla® - rFVIII-single Chain to treat Hemophilia A

10.20am

Dr. Jeremy Fry

ProImmune, UK

An integrated approach to managing immunogenicity risk and drug immune modulation

11.00am

Coffee, tea and networking

11.30am

Dr. Bartek Zuber

Swedish Orphan Biovitrum, Sweden

Immunogenicity assessment for Affibody-Fc fusion therapeutics

12.10pm

Dr. Nicky Cooper

Peptinnovate, UK

Progression of a Mycobacterium tuberculosis derived peptide into clinical studies

12.40pm

Lunch provided

2.00pm

Dr. Tim Hickling

Pfizer, USA

Applying in vitro immunogenicity assays to predict clinical immunogenicity

2.40pm

Dr. Timm Jessen

Topas Therapeutics, Germany

Generating antigen-specific immune tolerance

3.20pm

Coffee, tea and networking

3.40pm

Dr. Sophie Sibéril

Centre de Recherche des Cordeliers, UPMC, France

Analysis of peripheral T-cell compartments in high-grade Follicular Lymphoma patients treated with rituximab-based regimens

4.20pm

Dr. Yu-Chan Chao

Academia Sinica, Taiwan

Display of foreign surface antigens on baculovirus as pseudotyped viruses for immunological studies and applications

5.00pm

Networking drinks reception

Friday 24 March 2017

8.30am

Arrival, registration and refreshments

9.00am

Prof. Tim Elliott

University of Southampton, UK

Applying mechanism based computational models to CTL epitope prediction

9.40am

Prof. Mark Exley

Agenus, USA

Phosphopeptide Neoantigens for Tumor Immunity: Novel therapeutic options

10.20am

Dr. Nikolai Schwabe

ProImmune, UK

Epitope identification and clinical trial immune monitoring in immune oncology programmes

11.00am

Coffee, tea and networking

11.30am

Prof. Miles Carroll

Public Health England, UK

Understanding the immune response to EBOV during acute disease and in EVD survivors

12.10pm

Dr. Katie Ewer

University of Oxford, UK

Identification of human T cell epitopes in the Ebolavirus Glycoprotein following vaccination with viral vectors

12.50pm

Lunch provided

2.00pm

Prof. Christine Falk Medizinische Hochschule Hannover, Germany

Precision Medicine in Transplantation - immune monitoring for the discrimination of GVHD, rejection and CMV infection

2.40pm

Prof. Farzin Farzaneh

King's College London, UK

Therapeutic Cancer Vaccines

3.20pm

Dr. Menna Clatworthy

University of Cambridge, UK

Immune complexes modulate immune highways and DC trafficking

4.00pm

Summary and Conference close

How will I benefit?

  • Education

    • Learn the key issues facing drug developers

    • Be informed of the latest strategies for pre-clinical and clinical immune modulation

    • Quality by Design in drug development

    • Be informed of the latest technologies to keep ahead of the competition

    • Case studies

  • Network

    • Exchange new ideas

    • Meet potential collaborators

    • Discuss current and developing challenges

    • Meet like-minded scientists from other organizations, and to help shape the future of your own R&D programs.

Feedback from previous conferences:

“Mastering Immunogenicity captured the breadth and depth of immunogenicity issues faced by industry today” (Tim Hickling, Pfizer)

“I also had a great time during the meeting. It was truly excellent in content and organization.” (Julio Delgado, University of Utah)

“It was a terrific event, with excellent speakers and great networking/brainstorming opportunities at the breaks and with the roundtable” (Valerie Quarmby, Genentech)

"Great first experience. I enjoyed the breadth of topics" (Laurent Malherbe, Eli Lilly)

 “Great speakers with diverse topics. I enjoyed the deep science and also the opinions from experts in the field” (Xiaoying Chen, Pfizer)

 "Covered a diverse array of subjects. I enjoyed the networking opportunities” (Shinu John, Moderna Therapeutics)

"Excellent event" (George Gunn, Janssen R&D)

"Really liked the interactive environment. In-depth discussions with very relevant colleagues"

 "I really enjoyed the very good quality, sparkling diversity, but still keeping focus"

Conference Venue

The City of Oxford

 

Picture: Nasir Hamid

A fitting venue for our conference, Oxford is a world leading center in science research and education.

Situated approximately 50 miles north-west of London, modern Oxford owes much to the University, which was founded in 1096 and is the oldest university in the English speaking world. Visitors to the city can tour splendid British architecture, including such icons as the mid-18th century Radcliffe Camera, the Bodleian Library and the Bridge of Sighs.

For further information about Oxford and the surrounding area browse, “Experience Oxfordshire”, the official tourism website for Oxfordshire.

http://experienceoxfordshire.org  

 

 

Wolfson College    

 

 

Wolfson College, part of the University of Oxford, is situated within 13 acres of stunning riverside gardens. It offers a tranquil rural retreat just a short walk from Oxford city centre. Wolfson is an all-graduate college with students from 75 nations. It was founded in 1965 by Sir Isaiah Berlin, the influential political philosopher.

 

The conference itself will take place in Wolfson’s award-winning Leonard Wolfson Auditorium.  This building is very striking architecturally, with a remarkably shaped ceiling giving excellent acoustics, and chestnut-lined interior creating a sense of elegance and light.

 

Accommodation
Although no accommodation is available at the college, we would recommend the following establishments just a short distance away:

The Best Western Linton Lodge Hotel: www.bw-lintonlodgehotel.co.uk (2 minute walk)
Parklands Bed & Breakfast:
www.parklandsoxford.co.uk (5 minute walk)
Cotswold Lodge Hotel:
www.cotswoldlodgehotel.co.uk (10 minute walk)

Travel
Oxford is 56 miles (90km) north-west of London, with excellent bus and rail services.

By Air
There are 3 major international airports (London Heathrow, LHR; London Gatwick, LGW; Birmingham International, BHX) within 2 hours travel time. The simplest and best option if you are flying to any of these airports is to take the regular bus service direct to Oxford City. See
http://airline.oxfordbus.co.uk/timetables/  for details.
Airport Taxi Transfers: Pryors (+44 1235 812346).

By Road
The city is well served by public transport but the historic nature of the city center means parking spaces are in very short supply. There is no parking available at the conference venue. We would recommend parking at the Water Eaton Park and Ride or Peartree Park and Ride. Both are just a 15-20 minute bus ride to the conference.

By Rail
The closest rail stations are Oxford (serving direct trains from London Paddington) and Oxford Parkway (serving direct trains from London Marylebone). Both stations are a 15-20 minute direct bus ride / 10 minute taxi ride from the venue. See
www.nationalrail.co.uk for more details.

For all Conference Enquiries please contact:

enquiries@proimmune.com

Telephone (toll free): USA & Canada +1 888 505 7765
All other countries +44 (0) 870 042 7279